Whole genome assembly analysis

For organisms with no reference genomes or highly dynamic genomes, dna-sequencing data analysis starts with assembling a genome de novo. genome assembly benefits from deep whole-genome sequencing. An assembled genome is annotated based on sequence homology, predicted gene sequences and, if available, rna-sequencing data from the same organism. if annotated genomes for close relative species exist, the annotation can be improved by transferring gene information to the newly assembled genome.